Atherosclerosis Reduced by Targeted Nanoparticle “Drones” in Animals

Boston, MA, & New York, NY (Feb.18, 2015) – Nanometer-sized “drones” that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, according to a study in preclinical models by scientists at Brigham and Women’s Hospital (BWH) and Columbia University Medical Center (CUMC). The findings are published in the February 18 online issue of Science Translational Medicine.

Source: Columbia University Medical Center (http://www.cumc.columbia.edu/)

“The inflammation resolving targeted nanoparticles have shown exciting potential not only for the potential treatment of atherosclerosis as described here, but also other therapeutic areas including wound repair, for example, as described in the Feb. 9 online issue of Journal of Clinical Investigation, in addition to other applications currently underway with our collaborators,” Farokhzad said. “I’m optimistic that with additional animal validation we will also consider the human testing of the inflammation resolving targeted nanoparticles for a myriad of unmet medical needs–these are exciting times in medicine and the future of nanomedicine is incredibly bright.”

Video/Photo: Yuriy Svidinenko, NonoBot Models (http://www.nanobotmodels.com/)

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