Immune-suppressant vaccine blocks HIV infection in monkeys: human trials planned

Rhesus Macaques.

the medically specific terminology and scientific details were taken in large part from NAM and Aidsmap, an excellent source and knowledge, science and support. 

 

A novel vaccine has been shown to completely block rectal infection of SIV, the monkey equivalent of HIV, in rhesus Macaques. The same vaccine was also shown to produce rapid re-suppression of viral load ( the level of HIV in the blood) in monkeys who were previously infected with SIV. The vaccine program is a collaboration between scientists at the French Institute for Research into Cancer and HIV Vaccines at Paris-Descartes University and ones at the Chinese Tropical Medicine Institute at the University of Chinese Medicine in Guangzhou.

 

 

Following the study’s outstanding success in primates two initial safety trials are now planned in humans. According to aidsmap.com: in one trial, HIV-negative volunteers at low risk of HIV will be given the vaccine to see if it stimulates the same immune- and virus-suppressant responses. In the other trial, HIV-positive volunteers on fully-suppressive antiviral therapy will be given the vaccine and then taken off six months later if test tube results suggest the vaccine has produced such responses.

 

The vaccine consisted of inactivated SIV administered alongside doses of familiar bacteria – in the first case the TB-suppressant bacterium BCG, and subsequently with gut bacteria of the Lactobacillusgenus, including one type commonly used in probiotic supplements. This suggests that if human studies replicate the success seen in monkeys (by no means assured in vaccine studies) the vaccine could be administered in a drink.

 

How does it work:

The researchers designed the vaccine according to  a long-held hypothesis that conventional vaccines ( that rely on stimulating an immune response to a microbe in advance of exposure to it) could not work in preventing the spread of HIV, as this virus uses the very cells that proliferate in an immune response – primarily CD4 T-cells – as the ones it chooses to reproduce in. Therefore with an HIV vaccine the challenge for researchers would therefore be to induce the body to recognize HIV but not to mount a proliferative response to it. This could work if the body is induced to respond to HIV as if it was harmless – to induce so-called ‘immune tolerance’ to it.    

[caption id="attachment_669" align="alignnone" width="300"]a healthy human T-Cell a healthy human T-Cell[/caption]

 

34 Comments

  • […] without the authenticity guarantee. To avoid confusion and scams, the genuine Hoodia appetite suppressant can only be obtained exclusively from its HoodiaP57 […]

  • Reply March 29, 2017

    Skrota bil Göteborg

    … [Trackback]

    […] Read More: rawscience.tv/immune-suppressant-vaccine-blocks-hiv-infection-in-monkeys-human-trials-planned/ […]

  • Reply March 29, 2017

    motor club of america

    … [Trackback]

    […] Informations on that Topic: rawscience.tv/immune-suppressant-vaccine-blocks-hiv-infection-in-monkeys-human-trials-planned/ […]

  • Reply April 18, 2017

    dancing with the rose

    What’s up to all, as I am really keen of reading this web site’s post to be updated daily.
    It carries fastidious stuff.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 20, 2017

    Car Rentals in Gensan

    Hi there, I want to subscribe for this web site to get most recent updates, so where can i do it please help out.
    1d274c00d2214f1780232c6fb61aca1a

  • It’s actually a great and useful piece of information. I’m satisfied that you shared
    this useful information with us. Please stay us informed like this.
    Thank you for sharing.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 20, 2017

    General Santos City

    Heya are using WordPress for your site platform?
    I’m new to the blog world but I’m trying to get started and
    set up my own. Do you need any html coding expertise to make
    your own blog? Any help would be greatly appreciated!
    1d274c00d2214f1780232c6fb61aca1a

  • I have read so many content on the topic of the blogger lovers however this piece of writing is genuinely
    a fastidious piece of writing, keep it up.
    1d274c00d2214f1780232c6fb61aca1a

  • I have read so many articles about the blogger lovers however this
    article is genuinely a fastidious piece of writing, keep it up.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 21, 2017

    pills

    Hello! I could have sworn I’ve been to this site before but after browsing through many of
    the posts I realized it’s new to me. Anyhow, I’m certainly delighted I stumbled upon it and I’ll be book-marking it and checking back regularly!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 22, 2017

    poker

    It’s the best time to make some plans for the future and it’s time to be happy.
    I have read this post and if I could I want to suggest you some interesting things or tips.
    Maybe you can write next articles referring to this article.
    I desire to read more things about it!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 23, 2017

    SSGSS Goku Vs 17

    Yes! Finally someone writes about stock trading accounts.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 23, 2017

    www.youtube.com

    Hi to all, how is the whole thing, I think every one is
    getting more from this web site, and your views are pleasant for new people.
    1d274c00d2214f1780232c6fb61aca1a

  • Hi! Do you use Twitter? I’d like to follow you if that would be
    okay. I’m definitely enjoying your blog and look forward to new updates.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 27, 2017

    adam and eve sex store

    Really no matter if someone doesn’t be aware of after that its up to other users that
    they will help, so here it takes place.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 27, 2017

    Nippleclamps

    Very nice post. I certainly appreciate this
    website. Stick with it!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply April 29, 2017

    vibrating butt plug

    Wonderful blog! I found it while searching on Yahoo News.
    Do you have any tips on how to get listed in Yahoo News?
    I’ve been trying for a while but I never seem to get there!
    Appreciate it
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 1, 2017

    youtube.com/

    Great blog here! Also your web site loads up very fast! What host are you using?
    Can I get your affiliate link to your host? I wish my web site loaded up
    as quickly as yours lol
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 2, 2017

    massage vibrator

    great points altogether, you simply received a new
    reader. What could you suggest in regards to your post that you made some days in the past?
    Any certain?
    1d274c00d2214f1780232c6fb61aca1a

  • Hello there! This post could not be written any better!
    Going through this post reminds me of my previous roommate!
    He continually kept preaching about this. I will forward this post to him.
    Pretty sure he’ll have a great read. I appreciate
    you for sharing!
    1d274c00d2214f1780232c6fb61aca1a

  • Good article. I absolutely appreciate this website. Stick with it!
    1d274c00d2214f1780232c6fb61aca1a

  • Fantastic site. A lot of helpful info here. I am sending it to several friends ans also sharing in delicious.
    And naturally, thanks in your effort!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    YouTube video

    Oh my goodness! Incredible article dude! Thank you, However I am going through difficulties with your RSS.
    I don’t know the reason why I can’t subscribe to it. Is there anyone else getting the
    same RSS problems? Anyone who knows the answer can you kindly respond?

    Thanks!!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    YouTube video

    Hello there! I could have sworn I’ve been to this blog before but
    after browsing through some of the posts I realized it’s new to me.
    Anyways, I’m certainly happy I stumbled upon it and I’ll be book-marking it and checking back
    frequently!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    YouTube video

    I know this if off topic but I’m looking into starting
    my own weblog and was curious what all is required to get
    setup? I’m assuming having a blog like yours
    would cost a pretty penny? I’m not very web smart so I’m not
    100% certain. Any recommendations or advice would be greatly appreciated.

    Many thanks
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    www.youtube.com

    I always used to study article in news papers but now as I am a user
    of web therefore from now I am using net for articles,
    thanks to web.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    YouTube video

    It’s enormous that you are getting thoughts from this paragraph as well as from our discussion made at this place.
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    www.youtube.com

    Awesome things here. I am very happy to look your post.
    Thanks a lot and I’m taking a look forward to touch
    you. Will you kindly drop me a mail?
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    YouTube video

    This is my first time pay a quick visit at here and i am truly happy to
    read everthing at single place.
    1d274c00d2214f1780232c6fb61aca1a

  • You should be a part of a contest for one of the finest blogs on the net.
    I will highly recommend this blog!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 5, 2017

    Allison

    Hey I know this is off topic but I was wondering if you knew of any widgets
    I could add to my blog that automatically tweet my newest twitter updates.

    I’ve been looking for a plug-in like this for quite some
    time and was hoping maybe you would have some experience
    with something like this. Please let me know if you run into anything.
    I truly enjoy reading your blog and I look forward to your
    new updates. http://leannek7401727907.blog.fc2.com/blog-entry-2.html
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 6, 2017

    breasts

    Way cool! Some very valid points! I appreciate you writing this post plus the rest
    of the website is also really good.
    1d274c00d2214f1780232c6fb61aca1a

  • Wow, fantastic weblog format! How lengthy have you
    been blogging for? you make running a blog glance easy.

    The overall look of your website is magnificent, as neatly as the content material!
    1d274c00d2214f1780232c6fb61aca1a

  • Reply May 31, 2017

    www.youtube.com

    Usually I don’t read article on blogs, however I wish to
    say that this write-up very forced me to take a look at and do it!

    Your writing taste has been amazed me. Thank you, quite great post.
    1d274c00d2214f1780232c6fb61aca1a

Leave a Reply Click here to cancel reply.

Leave a Reply to www.youtube.com Cancel reply